Biology

Biology

Spotlight on Student Research

 

 

Cathy Soliva recently earned her Master’s Degree in Biology under the guidance of Dr. Cindy Malone, performing her graduate research in the CSUN-UCLA Bridges to Stem Cell Research Program. Cathy studied endometrial regeneration in the laboratory of Dr. Sanaz Memarzadeh at UCLA. Her hypothesis was that there was one cell type rather than two cell types that were the dual progenitor stem cell for the epithelium and stroma in the endometrium. Her study focused on determining whether a specific subset of human endometrial cells that co-expressed several markers for epithelia and stroma were in fact the stem cells responsible for regenerating the endometrium each month in women. These cells are rare, found in the eutopic endometrium and pelvic washings of women with and without endometriosis. Cathy showed that the cells she isolated produced epithelia and stroma when plated as 10,000 cells and as single cells in in vitro cell culture. She showed that these cells regenerated the correct type of epithelial tissue in an in vivo model. Future aims include isolating progenitors from women with and without endometriosis to see if there is a difference between progenitor cells that cause endometriosis and progenitor cells that do not. Cathy began her doctorate program in Physical Therapy here at CSUN last fall.