Published papers

* CSUN student authors


43.T-tubule remodeling and increased heterogeneity of calcium release during the progression to heart failure in intact rat ventricle.

Jasleen Singh, Varderes Barsegyan*,..., JA Waserstrom


42. Triggered intracellular calcium waves in dog and human left atrial myocytes from normal and failing hearts

GL Aistrup, R Arora, S Grubb, S Yoo, B Toren, M Kumar, A Kunamalla, ...
Cardiovascular Research 113 (13), 1688-1699


41. Stochastic spontaneous calcium release events and sodium channelopathies promote ventricular arrhythmias.

with Fernando Campos, Eward Vigmond and Gernot Plank

Chaos 27, 093910 (2017).


40. Mechanism for Triggered Waves in Atrial Myocytes

with Gary Aistrup and Andy Wasserstrom

Biophysical Journal 113, August 8 2017.


39. Nonlinear signaling on biological networks: the role of stochasticity and spectral clustering

Gonzalo Hernandez*, Jesse Meyers*, Enric Alvarez-Lacalle, and Yohannes Shifeaw

Phys. Rev. E 95, 032313 (2017)


38. Nonlinear onset of calcium wave propagation in cardiac cells

Yohannes Shiferaw

Phys. Rev. E 94, 032405 (2016).


37. Role of connectivity and fluctuations in the nucleation of calcium waves in cardiac cells

Gonzalo Hernandez*, Enric Alvarez-Lacalle, and Yohannes Shifeaw

Phys. Rev. E 92, 052715 (2016).


36. Calcium alternans is a global order-disorder phase transition. Robustness on Ryanodine Receptor dynamics.

Enric Alvarez-Lacalle, Angelina Penaranda, Inmaculada Cantalapiedra, Yohannes Shiferaw and Blas Echebarria.

Computing in Cardiology, 2015 (329-332).


35. Slow [Na]i Changes and Positive Feedback Between Membrane Potential and [Ca]i Underlie Intermittent Early Afterdepolarizations and Arrhythmias

Yuanfang Xie, Zhandi Liao, Eleonora Grandi, Yohannes Shiferaw and Donald M. Bers

Circ Arrhythm Electrophysiol. 2015 Sep 25. pii: CIRCEP.115.003085. [Epub ahead of print]


34. Stochastic spontaneous calcium release events trigger premature ventricular complexes by overcoming electrotonic load.

Campos FO, Shiferaw Y, Prassl AJ, Boyle PM, Vigmond EJ, Plank G.

Cardiovasc Res. 2015 May 12. pii: cvv149. [Epub ahead of print]


33. Approximate analytical solutions for excitation and propagation in cardiac tissue

D'Artagnan Greene* and Yohannes Shiferaw Phys. Rev. E 91, 042719 – Published 30 April 2015


32. Calcium alternans is due to an order-disorder phase transition.

Enric Alvarez-Lacalle, Blas Echebarria, Jon Spalding*, Y. Shiferaw. Phys. Rev Lett. 114 (108101), 2015.


31. Formation of spatially discordant alternans due to fluctuations and diffusion of calcium (paper).

Sato D, Bers DM, Shiferaw Y. PLoS One. 2013 Dec 31;8(12)


30. Tissue Structure and Ca2+-Mediated Ectopic Beats.

Campos FO, Shiferaw Y, Plank G. Biomed Tech (Berl). 2013 Sep 7.


29 The timing statistics of spontaneous calcium release in cardiac myocytes.

Asfaw M, Alvarez-Lacalle E, Shiferaw Y. PLoS One. 2013 May 17;8(5):e62967


28. Intracellular Ca2+ waves, afterdepolarizations, and triggered arrhythmias.

Shiferaw Y, Aistrup GL, Wasserstrom JA. Cardiovasc Res. 2012 Aug 1;95(3):265-8.


27. Zhiheng Jia, Harold Bien, Yohannes Shiferaw, Emilia Entcheva . Cardiac Cellular Coupling and the Spread of Early Instabilities in Intracellular Ca2+. Biophysical Journal 102(6) pp. 1294 - 1302 . 2012.


26. Chen W, Asfaw M, Shiferaw Y. The statistics of calcium mediated focal excitations on a one dimensional cable. Biophysical Journal. 2012. 102(3) pp. 461-471.


25. Asfaw M, Shiferaw Y. Exploring the dynamics of dimer crossing over a Kramer's type potential. J. Chem. Phys. 2012. Jan 14;136(2):025101.


24. A Mathematical Model of Spontaneous Calcium Release. Chen W,Aistrup GL,Wasserstrom JA, Shiferaw Y. Am J Physiol Heart Circ Physiol. 2011 May;300(5):H1794-805.


23. Variability in Timing of Spontaneous Calcium Release in the Intact Rat Heart Is Determined by the Time Course of Sarcoplasmic Reticulum Calcium Load. Wasserstrom JA, Shiferaw Y, Chen W, Ramakrishna S, Patel H, Kelly JE, O'Toole MJ, Pappas A, Chirayil N, Bassi N, Akintilo L, Wu M, Arora R, Aistrup GL. Circ Res. 2010 Sep 9.


22.  Wei Chen, Andrew Wasserstrom, Yohannes Shiferaw. Role of Coupled Gating between Cardiac Ryanodine Receptors in the Genesis of Triggered Arrhythmias.     Am J Physiol Heart Circ Physiol 297: H171-H180, 2009.


21.  Gary Aistrup*, Yohannes Shiferaw*, Alan Kadish, and Andrew Wasserstrom. (*shared first authorship) Mechanisms underlying the formation and dynamics of subcellular calcium alternans in the intact heart.  Circ. Res: 104; 639-649, 2009.


20.  Aman Mahajan*, Daisuke Sato*, Yohannes Shiferaw*, Lai-Hua Xie, Riccardo Olcese, Ali Baher, Jim Yang, Alain Karma, Peng-Sheng Chen, Alan Garfinkel, Zhilin Qu, and James N. Weiss. (*shared first authorship)  Modifying L-type Calcium Current Kinetics as a Novel Antifibrilatory Strategy.   Biophys J., 2008, Jan 15; 94(2): 411-423. 


19.  *Mahajan A, *Shiferaw Y, Sato D, Baher A, Olcese R,  Xie L, Yang JM, PS Chen, Karma, A Alan Garfinkel A, Z Qu  Z and Weiss JN.  (*shared first authorship)  A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates.  Biophys J. 2008, Jan 15; 94(2):392-410.


18. Robert Rovetti, Kunal Das, Alan Garfinkel, and Yohannes Shiferaw.    Macroscopic consequences of calcium signaling in microdomains: a first passage time approach.  Phys. Rev. E.  76, Nov 2007.


17.  *Gudzenko V., *Shiferaw Y., Savalli N., VyasR., Weiss JN, and Olcese R.  (*shared first authorship)  Influence of Channel Subunit Composition on L-type Ca2+ Current Kinetics and Cardiac Wave Stability.  Am  J. Physiol. Heart Circ. Physiol.  Sept. 2007, 293(3), H1805-15. 


16.  Qu Z, Shiferaw Y, Weiss JN.  Nonlinear dynamics of cardiac excitation-contraction coupling: an iterated map study.   Phys Rev E.  2007 Jan; 75(1 Pt 1):011927.


15.  *Sato D, *Shiferaw Y, Qu Z, Garfinkel A, Weiss JN, Karma A.   Inferring the cellular origin of voltage and calcium alternans from the spatial scales of phase reversal during discordant alternans.   (*shared first authorship)   Biophys J.  (letters) 2007 Feb 15; 92(4):L33-5. 


14.  *Hayashi H, *Shiferaw Y, Sato D, Nihei M, Lin SF, Chen PS, Garfinkel A, Weiss JN, Qu Z.  (*shared first authorship)  Dynamic origin of spatially discordant alternans in cardiac tissue.  Biophys J. 2007 Jan 15; 92(2):448-60.


13.  Shiferaw Y, Qu Z, Garfinkel A, Karma A, Weiss JN.  Nonlinear dynamics of paced cardiac cells.  Ann NY Acad Sci.  2006 Oct; 1080:376-94.


12.  *Sato D, *Shiferaw Y, Garfinkel A, Weiss JN, Qu Z,  Karma A.  (*shared first authorship)  Spatially discordant alternans in cardiac tissue: role of calcium cycling.   Circ Res.  2006 Sep 1; 99(5): 520-7.


11.  Weiss JN, Karma A, Shiferaw Y, Chen PS, Garfinkel A, Qu Z.    From pulsus to pulseless: the saga of cardiac alternans.    Circ Res. 2006 May 26; 98(10):1244-53. 


10.  Y. Shiferaw, D. Sato, and A. Karma.   Subcellular Turing instability mediated by voltage and calcium diffusion in cardiac cells.     Proc Natl Acad Sci USA. 2006 Apr 11; 103(15):5670-5. 


9.  Y. Shiferaw, D. Sato, and A. Karma.   Coupled dynamics of voltage and calcium in paced cardiac cells.  Phys. Rev. E  71  021903 (2005).


8.  Y.Y. Golschmidt and Y. Shiferaw.   Localization of polymers in random media: analogy with quantum particles in disorder.  Book chapter in Statistics of linear polymers in disordered media, Edited by Bikas Chakravarti, Elsevier (Amsterdam) 2005.


7.  C. Stubbins, K. Das, and Y. Shiferaw.   Low-lying energy levels of the hydrogen atom in a strong magnetic field.   J. Phys. B: At. Mol. Opt. Phys. 37 2201-2209.


6.  Y. Shiferaw, M.A. Watanabe, A. Garfinkel, J.N. Weiss, and A. Karma.    Model of intracellular calcium cycling in ventricular myocytes.   Biophys. J. 2003: 3666-3686.


5.  Y. Goldschmidt and Y. Shiferaw.   Polymers with self-avoiding interactions in random medium: a localization-delocalization transition.   Eur.  Phys. J.  B 32, 1 (2003). 


4.  Y. Goldschmidt and Y. Shiferaw.   Localization of polymers in a finite medium with fixed random obstacles.    Eur. Phys. J. B 25,  351 (2002).


3.  Y. Shiferaw and Y. Goldschmidt.  Localization of a polymer in random media: relation to the localization of a quantum particle.   Phys.  Rev. E 63, 051803 (2001).


2.  Y.  Shiferaw and Y. Goldschmidt.   Solvable model of a polymer in random media with long ranged disorder correlations.    Journal of Physics A: Math. Gen. 33, 4461 (2000).


1.  G. Adkins and Y. Shiferaw.   Two-loop corrections to the orthopositronium and parapositronium decay rates due to vacuum polarization.  Phys. Rev. A. 52, 2442 (1995).