ATP SYNTHASE SITES FOR BIOCHEMISTRY
Email Dr.
Sandra L. Jewett is any link is not working properly.
(updated 4-17-13)
1997 Nobel Prize to Paul Boyer http://www.nobel.se/chemistry/laureates/1997/
**ANIMATED
MOVIES** DIRECT!
http://users.soe.ucsc.edu/~hongwang/Project/ATP_synthase/
http://www.cse.ucsc.edu/~hongwang/ATP_synthase.html
(See also Science
Vol 290 (11/24/2000) pp 1555-1558.)
***ANIMATED
MOVIE OF H+ PUMPING AND ATP SYNTHESIS
See other movies and pictures from Dr. Junge's webpages
http://www.biologie.uni-osnabrueck.de/biophysik/junge/Media.html
Function and Structure
*Animated view
of active sites**
http://rsb.info.nih.gov/NeuroChem/biomach/ATPsyn.html#ref1
This web site contains a short description of the ATP Synthase structure, its catalytic function, and an animated cartoon of the F1 subunit.
References
Abrahams, J. P., Leslie,
A. G., Lutter, R., and Walker J. E. (1994). Structure at
2.8 Å resolution of F1-ATPase from bovine heart mitochondria.
Nature 370: 621-628.
TUTORIAL ON BINDING CHANGE
MECHANISM (this tutorial is not available as of 5/03/03)
http://www.biochem.mcw.edu/~herman/science_ed/Pages/atpase/flash/atpase1.html
SIMPLE MOVIES OF PROTON GRADIENT
AND ATP SYNTHESIS
http://www.sp.uconn.edu/~terry/images/anim/ATPmito.html
http://www.life.uiuc.edu/crofts/bioph354/lect10.html
This web site has material on ATP synthase structure, function, subunit composition, catalytic mechanism, enzyme kinetics, and proton translocation. It has twelve different links to other web pages including the University of California at Berkeley at Hongyun Wang’s home page.
Refereces
a. Sabbert, D., Junge, W. (1997). Stepped versus continuous
rotatory motors at the molecular scale. Proc. Natl. Acad. Sci.
(U.S.) 94: 2312-2317. b. Sabbert, D., Engelbrecht,
S., Junge, W. (1997). Functional and idling rotatory motion within
F-1-ATPase. Proc. Natl. Acad. Sci. (U.S.). 94: 4401-4405.
c. Hasler, K.., Engelbrecht, S., Junge, W. (1998).
Three-stepped rotation of subunits gamma and epsilon in single
molecules of F1-ATPase revealed by polarized confocal fluorometry.
FEBS Lett. 426: 301-304.
http://www.nobel.se/chemistry/laureates/1997/
This web site reviews the 1997 Nobel Prize in Chemistry won by Professor Paul D. Boyer, University of California, Los Angeles, USA.
References
Boyer, P. D. (1993).The
binding change mechanism for ATP synthase - Some probabilities
and possibilities. BBA. 1140: 215-250.
Abrahams, J. P., Leslie,
A. G., Lutter, R., and Walker J. E. (1994). Structure at 2.8 Å
resolution of F1-ATPase from bovine heart mitochondria. Nature
370: 621-628.
Other ATP Synthase Web sites:
http://www.ukans.edu/~mb/bcmpcb/richter.html
For reference publications from the
University of Kansas.
See application of F1 subunit in nanomolecular technology:
http://www.res.titech.ac.jp/seibutu/nature/f1rotate.html (This site may be busy)
A fluorescent Actin filament motion
picture by Masasuke Yoshida. Institute of Technology, Japan.
http://www2.taylor.edu/upland/departments/biology/authorware/
This site has other useful information
in addition to the pictures of ATP synthase and other Biochemistry
subjects.
Related Articles
Razake-Jolly, D., Rigoulet,
M., Guering, B. (1994). Mutations in the hydrophobic domains of
ATP Synthase subunit 4 of Yeast Mitocondia disturbs coupling between
proton translocation and catalysis. Biochemistry 33: 9684-9691.
Van Walraven, H. S., Scholts,
M., C., Koppenaal, F., Bakels, R. A., Krab, K. (1990). Dependence
of the proton translocation stoichiometry of cyanobacterial and
chloroplast Hsup + -ATP synthase on the membrane composition.
BBA. 1015: 425-434.
These materials were first
developed by
Luis Muñoz
Chemistry 499
Fall 1998
California State University Northridge
Advisor: Dr. Sandra Jewett