Project ID: |
4002 3666 |
| Project Title: | Modulation of Gluccocorticoid-Evoked Lymphocyte Apoptosis by BTG1 |
Principal Investigator(s): |
Rheem Medh |
| College/Department: | College of Science & Mathematics / Department of Biology |
Sponsoring Agency: |
National Institute of Health |
Award Amount: |
$214,500 |
Matching Amount: |
0 |
Indirect Cost: |
$64,500 (43% TDC) |
Start Date: |
04/01/07 |
End Date: |
03/31/10
|
| CFDA # : | 93.847 |
Type of Project : |
Research
|
| Abstract: |
|
| Links: | Apoptosis is a form of physiological cell death essential for maintaining normal health, and is triggered by altered expression or funtion of mulitple genes, one of them being Btg1, a gene that has been shown to inhibit cell proliferation. Diseases such as Alzheimer's neurodegeneration, autoimmunity, immunodeficiency, osteoporosis, cancer, etc are conditions where apoptosis may be a contributing factor. This application proposes studies to understand the role of Btg1 in growth inhibition and apoptosis of T-leukemic cells.
|
© The University Corporation
- Sponsored Programs-
18111 Nordhoff Street Northridge, California 91330-8309 - Phone (818) 677-2698 - Fax (818)677-2671 - Email gjahn@csun.edu