
Jeffrey A. Charonnat
ASSOCIATE PROFESSOR
Department of Chemistry and Biochemistry
California State University, Northridge
Northridge, California, 91330-8262
telephone:
(818) 677-2109
e-mail:
jeff.charonnat@csun.edu
fax:
(818) 677-4068
Office: Science 4301
Weekly Schedule
EDUCATION
- B.S., Honors, Stanford University, 1977
- Ph.D., Columbia University, 1984
COURSES TAUGHT
Chemistry 105, Principles of Chemistry
- Chemistry 331, Organic Chemistry I
- Chemistry 331L, Organic Chemistry I Laboratory
- Chemistry 332, Organic Chemistry II
- Chemistry 332L, Organic Chemistry II Laboratory
- Chemistry 333, Principles of Organic Chemistry I
- Chemistry 333L, Principles of Organic Chemistry I Laboratory
- Chemistry 334, Principles of Organic Chemistry II
- Chemistry 334L, Principles of Organic Chemistry II Laboratory
- Chemistry 433, Organic Analysis
- Chemistry 433L, Organic Analysis Laboratory
RESEARCH INTERESTS
Organic Chemistry
Professor Charonnat's current research is in the following areas of organic synthesis:
- The total synthesis of natural products,
- the development of new synthetic methodology and
- the synthesis of novel compounds of biochemical and pharmaceutical interest.
The first project is a highly stereo- and regio-controlled total synthesis of the GABA antagonist, (-)-anisatin. This natural product is a functionally complex sesquiterpene and one of very few naturally occurring beta-lactones. The second category includes studies on mild, selective Conia cyclizations. The third project is focused on the synthesis of novel, tethered cisplatin anticancer agents.
REPRESENTATIVE
PUBLICATIONS
- "Novel Application of the Intramolecular Prins Reaction: (-)-Anisatin Model Study," Charonnat, J. A., Nishimura, N., Travers, B. W. and Waas, J. R., Synlett (1996), 1162-1164.
- "Conjugate Addition of Lithium Diorganocuprate Reagents to the Enol Tosylate of a 1,2-Diketone," Charonnat, J. A., Mitchell, A. L. and Keogh, B. P., Tetrahedron Lett. (1990) 31, 315-318.
M. S. THESES
- Studies Directed Toward the Total Synthesis of the GABA Antagonist, (-)-Anisatin (1996) Nishimura, N.