Dept. of Chemistry & Biochemistry

18111 Nordhoff Street
Northridge, California 91330-8241

Phone: (818) 677-1200
Fax: (818) 677-4068M
E-mail: chemistry@csun.edu

Hours:
Mon-Fri: 8:00am-5:00pm

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Jeffrey A. Charonnat

Jeffrey A. Charonnat

ASSOCIATE PROFESSOR

Department of Chemistry and Biochemistry
California State University, Northridge
Northridge, California, 91330-8262

telephone: (818) 677-2109
e-mail: jeff.charonnat@csun.edu
fax: (818) 677-4068

Office: Science 4301

Weekly Schedule



EDUCATION

  • B.S., Honors, Stanford University, 1977
  • Ph.D., Columbia University, 1984

COURSES TAUGHT

  • Chemistry 105, Principles of Chemistry
  • Chemistry 331, Organic Chemistry I
  • Chemistry 331L, Organic Chemistry I Laboratory
  • Chemistry 332, Organic Chemistry II
  • Chemistry 332L, Organic Chemistry II Laboratory
  • Chemistry 333, Principles of Organic Chemistry I
  • Chemistry 333L, Principles of Organic Chemistry I Laboratory
  • Chemistry 334, Principles of Organic Chemistry II
  • Chemistry 334L, Principles of Organic Chemistry II Laboratory
  • Chemistry 433, Organic Analysis
  • Chemistry 433L, Organic Analysis Laboratory

RESEARCH INTERESTS

Organic Chemistry
Professor Charonnat's current research is in the following areas of organic synthesis:
  1. The total synthesis of natural products,
  2. the development of new synthetic methodology and
  3. the synthesis of novel compounds of biochemical and pharmaceutical interest.

The first project is a highly stereo- and regio-controlled total synthesis of the GABA antagonist, (-)-anisatin. This natural product is a functionally complex sesquiterpene and one of very few naturally occurring beta-lactones. The second category includes studies on mild, selective Conia cyclizations. The third project is focused on the synthesis of novel, tethered cisplatin anticancer agents.

REPRESENTATIVE PUBLICATIONS

  1. "Novel Application of the Intramolecular Prins Reaction: (-)-Anisatin Model Study," Charonnat, J. A., Nishimura, N., Travers, B. W. and Waas, J. R., Synlett (1996), 1162-1164.
  2. "Conjugate Addition of Lithium Diorganocuprate Reagents to the Enol Tosylate of a 1,2-Diketone," Charonnat, J. A., Mitchell, A. L. and Keogh, B. P., Tetrahedron Lett. (1990) 31, 315-318.

M. S. THESES

  • Studies Directed Toward the Total Synthesis of the GABA Antagonist, (-)-Anisatin (1996) Nishimura, N.