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Dept. Chemistry & Biochemistry
18111 Nordhoff Street
Northridge, California
91330-8262
Phone: (818) 677-3381
Fax: (818) 677-4068
E-mail: chemistry@csun.edu
Office: 2102 Eucalyptus Hall
Hours: Mon-Fri 8:00am-5:00pm

Department of Chemistry and Biochemistry
California State University, Northridge
Northridge, California, 91330-8262
telephone: (818) 677-2699
e-mail: eric.kelson@csun.edu
fax: (818) 677-4068
Office: Citrus Hall 3315
The research underway in the Kelson laboratories is focused on the development of bifunctional ketone transfer hydrogenation catalysts with potential application for environmentally friendly and deliberately specific pharmaceutical synthesis. These catalysts are polypyridine supported ruthenium complexes designed to bind substrates and support hydrogen transfer through inter-ligand interactions. The novel design of these catalysts also render them tolerant of oxygen and independent of basic co-catalysts. Efforts are underway to extend the inter-ligand interactions beyond simple steric strategies to achieve selectivity and enantioselectivity in ketone transfer hydrogenation. As part of this work, the Kelson group has also developed single-flask methodologies for preparing novel polypyridine ligands for our designer catalysts that may also have potential as anti-tumor agents.
Influence of Intramolecular Ligand Interactions on the Redox and Transfer Hydrogenation Chemistry of Ruthenium Polypyridyl Complexes (2006) Algarin, E.
Development and Investigation of Ru ahd Rh Dechlorination Catalysts (2005), Behroozi, M. Catalytic Dehydrogenation of Alcohols Using Ru Complexes (2004), Binderwalla, R.
Hydrogen Transfer Catalysts by a Polypyridine Ruthenium Complex Incorporating 7-Azaindolato Ligands (2004) Lazik, R. M.
Electrochemistry of Polypyridine Ruthenium Complexes Bearing 2-Pyridonato, 2-Pyrrolidinonato and 7-Azaindolato Ligands (2003) Zhu, M.
Development and Mechanistic Investigation of Homogeneous Ruthenium and Rhodium Catalysts for the Transfer Hydrogenation of Ketones (2002) Heine, M. A.
Ruthenium Based Catalysts for Base Assisted Alcohol Oxidation Reactions (2001) Phengsy, P. P.